About

Professor at the University of Brussels (ULB, Belgium) and Research Director of the Belgian National Fund for Scientific Research (F.N.R.S.). Her research focuses on the molecular and epigenetic mechanisms regulating transcriptional latency and reactivation from latency in 3 retroviruses: HIV-1 and two oncogenic retroviruses HTLV-I (human T cell leukemia/lymphoma virus type 1) and BLV (Bovine Leukemia Virus). Regarding HIV-1, one of the major objectives of her laboratory is to design, based on transcriptional mechanisms, novel strategies to reduce the pool of latent reservoirs to a level bearable by the host immune system.

Position
Researcher
Institution
University of Brussels

Linked Projects

Funded Research Project

Title: Heterogeneity of mechanisms responsible for HIV-1 gene silencing, WP1

Despite current effective and life-prolonging combination antiretroviral therapy (ART), HIV 1 can still not be cured and remission is not attainable for most persons. Indeed, the virus persists in people receiving ART and can produce active infection upon treatment interruption due notably to reactivation of viral expression from latently-infected cells, called HIV reservoirs. HIV-1 transcriptional… Continue reading Heterogeneity of mechanisms responsible for HIV-1 gene silencing, WP1

Country
France
Starting year
2022
Duration
3 years
Budget
1.1M€
Members/PIs involved
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