Position
Researcher
Institution
University of Strasbourg
Website
https://www.researchgate.net/profile/Olivier-Rohr

Linked Projects

Funded Research Project

Title: Heterogeneity of mechanisms responsible for HIV-1 gene silencing, WP1

Despite current effective and life-prolonging combination antiretroviral therapy (ART), HIV 1 can still not be cured and remission is not attainable for most persons. Indeed, the virus persists in people receiving ART and can produce active infection upon treatment interruption due notably to reactivation of viral expression from latently-infected cells, called HIV reservoirs. HIV-1 transcriptional… Continue reading Heterogeneity of mechanisms responsible for HIV-1 gene silencing, WP1

Country
France
Starting year
2022
Duration
3 years
Budget
1.1M€
Members/PIs involved

Carine Van Lint

Researcher - University of Brussels

Véronique Avettand-Fènoël

Researcher - Medical virologist - Institut Cochin - CNRS 8104 / INSERM U1016 / Université Paris Cité

Olivier Lambotte

Clinician - Kremlin-Bicêtre Hospital

Asier Sáez-Cirión

Researcher - Institut Pasteur

Olivier Rohr

Researcher - University of Strasbourg

Stephane de Wit

Clinician - Saint-Pierre Hospital Bruxelles
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Linked Publications

Inhibition of HIV-1 gene transcription by KAP1 in myeloid lineage

Ait-Ammar A, Bellefroid M, Daouad F, Martinelli V, Van Assche J, Wallet C, Rodari A, De Rovere M, Fahrenkrog B, Schwartz C, Van Lint C, Gautier V, Rohr O. Sci Rep. 2021 Jan 29;11(1):2692. doi: 10.1038/s41598-021-82164-w.PMID: 33514850 
Novel role of UHRF1 in the epigenetic repression of the latent HIV-1

Verdikt V, Bendoumou M, Bouchat S, Nestola L, Pasternak AO, Darcis G, Avettand-Fenoeld V, Vanhulle C, Aït-Ammar A, Santangelo M. Plant E, LeDouce V, Delacourt N, Cicilionytė A, Necsoi C, Corazza F, Passaes CPB, Schwartz C, Bizet M, Fuks F, Sáez-Cirión A, Rouzioux C, De Wit S, Berkhout B, Gautier V, Rohr O, Van Lint C

eBioMedicine 2022, Volume 79, 1039852022